The Bundang CHA Hospital research team analyzed over 2,000 pregnant women and found that the timing of taking low-dose aspirin is important for preventing preeclampsia. Pregnant women who took aspirin before 12 weeks of pregnancy had a 71% lower risk of preeclampsia and preterm birth compared to those who started taking it between 12 and 20 weeks. The research team explained that aspirin affects the placental formation process, so its effect is greater when taken in early pregnancy. However, since this study was a retrospective analysis, further prospective studies and clinical trials targeting various population groups are needed to confirm the efficacy and safety of starting aspirin before 12 weeks of pregnancy.